buprenorphine, prolonged-acting injection and diazepam both of those improve sedation. Keep away from or Use Alternate Drug. Restrict use to people for whom different remedy options are inadequate
Use Caution/Monitor. Ethinyl estradiol could inhibit the clearance of benzodiazepines that endure oxidation, thus expanding serum concentrations of concomitantly administered benzodiazepines.
Keep an eye on Carefully (1)ethinylestradiol will boost the stage or outcome of diazepam by System: decreasing metabolism.
Oral Valium may very well be made use of adjunctively in convulsive Ailments, even though it hasn't proved handy as the sole therapy.
Unique treatment have to be taken when Valium is utilized throughout labor and shipping and delivery, as substantial one doses may perhaps produce irregularities while in the fetal heart rate and hypotonia, weak sucking, hypothermia, and moderate respiratory melancholy while in the neonates.
If this is simply not feasible, give drug into tubing of the flowing IV Answer as shut as feasible to vein insertion
fedratinib will boost the amount or impact of diazepam by impacting hepatic enzyme CYP2C19 metabolism. Use Caution/Keep track of. Adjust dose of medicine which can be CYP2C19 substrates as needed.
fosaprepitant will boost the level or impact of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
diazepam will enhance the level or effect of tinidazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
primidone will reduce the extent or result of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
Coadministration of encorafenib with sensitive CYP3A4 substrates may possibly end in amplified toxicity or reduced efficacy of those agents.
Medication that have to have prior authorization. This restriction needs that distinct scientific criteria be met ahead of the approval of your prescription.
diazepam will improve the level or impact of tazemetostat by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
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